I updated the uBlock Origin Suggested Settings page again after i started seeing ads in YouTube videos. UN! AC! CEPTABLE! Turns out the AdGuard filters don't block these ads, so i disabled them and re-enabled the Easy filters.
IMPORTANT: The caveat with the Easy filters is the CSP issue. If you don't know what that is, don't worry about it, just know that if you're using both uBlock and uMatrix, you need to disable and then re-enable uMatrix (about:addons) as soon as Firefox starts and before visiting any website where you don't want JS to run.